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NAD+ stands as a fundamental pillar of cellular biology and biochemistry, representing a master regulator of cellular energy metabolism, genomic stability, and longevity pathways that influences virtually every aspect of cellular function and organismal health

(2006b) evaluated the effects of local administration of VEGF165 on the semitendinosus tendon graft after ACL reconstruction and found that VEGF165 increased sheep knee laxity and decreased the stiffness of the grafted tendon 12 weeks after ACL reconstruction

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