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As potential therapeutics for MM, sdAbs such as WF211, MU1067, JK36, genetically fused to the hinge and Fc domains of human IgG1, have demonstrated the ability to elicit antibody-dependent cytotoxicity against CD38 + cancer cells [89]
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It works by mimicking ghrelin, the hunger hormone, to trigger GH secretion

The analogue 5-amino-1MQ was tested at concentrations from 600 M 30 nM

Medizinische Monatsschrift fur Pharmazeuten 2014;37:299
