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Evidence indicates that PGC-1 plays a pivotal role in the improvement of oxidative stress (Kaarniranta et al
Tirzepatide adds a second target, the GIP receptor, activating a dual pathway that supports fat metabolism and insulin sensitivity on top of appetite reduction
The resulting leakiness of microvessels in advanced unstable lesions can lead to hemorrhage of the plaque or rupture of the fibrous cap
doi: 10.3390/antiox12101798
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