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The mechanisms by which the ketone body D--hydroxybutyrate may improve the multiple cellular pathologies of Parkinson's disease

10.1080/20415990.2024.2363136 115 MoreS.BonnereauJ.WoutersD.SpotbeenX.KarrasP.RizzolloF.et al (2024)

This paper presents a first proof-of-concept that demonstrates the feasibility of activated effector/memory CD4+ helper T cells (CD4+ TEM cells) as carriers for the delivery of polymer nanoparticles across the BBB

Moreover, SIN has ability to penetrate the CNS and exert neuroprotective outcomes in vivo (136)
