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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Rockall AG, Sohaib SA, Evans D, Kaltsas G, Isidori AM, Monson JP, Besser GM, Grossman AB, Reznek RH

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These findings suggested that busulfan can significantly induce ROS creation and reduce antioxidants, leading to oxidative stress and lipid peroxidation in testicular tissue, which, in turn, can result in germ cell death, spermatogenesis impairment, and infertility (49)