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The widely repeated claim that it is ~ten-million-fold more potent than BDNF is a relative in-vitro spine-counting ratio, not a human effect, and key mechanism papers from the originating lab were retracted in 2025

Confusion between units, particularly mg and mcg, is the single most common source of dosing error in peptide research

Apply appropriate amount across entire face after cleansing and toning

Important factors to consider: Slow nerve regeneration rates Intricate cellular repair processes Impact of ongoing conditions like diabetes Multiple types of nerve damage Interaction with other body systems Varying causes of damage Want to understand your neuropathy better

Nov 1992;24(11):1290-7