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Description
Histamine was first identified in 1946 as the causative agent of the toxic effects of consuming poorly transported tuna, and for a long time histamine poisoning was associated almost exclusively with the consumption of spoiled fish [44,45]
In the exploration of therapeutic strategies for MIRI, combination drug therapy has shown distinct advantages (175,176)
J Biol Chem 2001;276:48562-71
It contains two conserved peptide motifs, DSGIS and DSAPGS, which are recognized by -transducin repeat-containing protein (-TrCP)
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