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They physically disrupt the electron transport chain, the series of protein complexes inside the mitochondria that generate ATP, leading to a catastrophic drop in cellular energy production

doi:10.1016/j.diabet.2016.09.005 Rena G, Pearson ER, Sakamoto K

Brain slice electrophysiology Mice were anaesthetized with isoflurane and then perfused with ice-cold oxygenated N-Methyl-D-glucamine (NMDG) artificial cerebrospinal fluid (ACSF) (20 mL) that contained (in mM): KCl (2.5), NMDG (93), NaHCO (30), NaHPO (1.2), glucose (25), HEPES (20), thiourea (2), Na-pyruvate (3), CaCl (0.5), Na-ascorbate (5), MgSO (10), and glutathione (3) (pH 7.37.4, 300305 mOsm)

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BPC-157 targets injured tissues directly, while TB-500 boosts cellular regeneration across the body