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Conversely, H 2 O 2 /O promotes CPT1 expression by activating PPAR, further enhancing fatty acid oxidation [190]

Bilirubin has antioxidant properties and can effectively remove peroxyl radicals, preventing lipid and lipoprotein oxidation, particularly LDL-C peroxidation

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Despite these common pathways, the initial mechanisms and clinical consequences diverge

While traditional retinoids remain the absolute gold standard for anti-aging and acne treatment, the latest skincare trends are introducing gentler, smarter pathways