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doi: 10.1016/j.cbpa.2012.10.016 15 LucRVergelyC

Collectively, these microbes contribute to carbohydrate fermentation by producing organic acids, support mineral absorption and bioavailability, help maintain epithelial barrier integrity, and modulate immune and metabolic pathways linked to inflammation, infection, and lipid homeostasis (29)

Administration of exogenous 1,25-(OH) 2 D 3 suppresses EAE progression through Rag-1-dependent lymphocyte-mediated mechanisms that restrict CNS infiltration of auto-reactive T cells and macrophages, promote apoptosis of inflammatory cells, and enhance survival of resident CNS cells, an effect associated with decreased macrophage accumulation within the CNS (Nashold et al., 2001

Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

(2010), Verma & Swamy (2015), Vaccari (2017), and reviewed by Sokolovic et al
