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It was developed as a synthetic version of Epithalamin, a peptide complex originally extracted from bovine pineal gland tissue

It is primarily used to treat vitamin B12 deficiency, which can lead to anemia, fatigue, and neurological symptoms

The most commonly treated muscles for synkinesis were the platysma, mentalis, orbicularis oculi, orbicularis oris, and levator labii superioris alaeque nasi on the affected side

This was associated with a reduction in activated microglia and an increase in the number of the newly-born neurons following indomethacin administration [100]

TB500 is classified as a performance-enhancing agent Use may result in disqualification, suspension, or sanctions It is detectable through advanced peptide biomarker testing Any peptide that promotes tissue repair, angiogenesis, or regeneration including thymosin beta4 derivatives is prohibited under current WADA guidelines. WADA Prohibited List 2024 If you are a tested athlete, even trace use of TB500 could result in a failed drug test and career-impacting consequences