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Another compound that was identified as potent BACH1-inhibitor was the phytocannabinoid cannabidiol (CBD), which induces nuclear export and degradation of the transcription factor ( In vitro models have confirmed CBDs antioxidant and anti-inflammatory properties, acting through HMOX-1 and inducing the downregulation of pro-inflammatory cytokines (Juknat et al., 2016

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Aliment Pharmacol Ther 57(3):313322

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GSH is a non-prescription antioxidant that is cheap to produce in pure form

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Similar results were observed in an in vitro experiment of NSCLC (Sun et al., 2020)

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3 Lapatinib for the treatment of HER2-overexpressing breast cancer

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