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Besides being the sole antioxidant enzyme able to repair lipid peroxides, GPX4 is a moonlighting protein that also regulate eicosanoid biosynthesis ( Hydroperoxides relevant to inflammation are those formed from arachidonic acid (AA) by stereoselective lipoxygenases

The Model group exhibited significantly higher fasting blood glucose levels (Figure 1C), HOMA-IR (Figure 1D) and FINS (Figure 1E), and ISI (Figure 1F) than that of the Control group

Artesunate inhibits epithelial-mesenchymal transition in non-small-cell lung cancer (NSCLC) cells by down-regulating the expression of BTBD7

Dangl, H

doi: 10.1128/CMR.00116-14 89 MeenaD