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Description
Glutathione can react with 5,5-dithiobis-(2-nitrobenzoic acid) (DTNB) to produce 2-nitro-5-mercaptobenzoic acid and glutathione disulfide (GSSG)

[PubMed 433937] 332

Although both theories are plausible no direct evidence for either has been demonstrated

These findings provide new molecular basis for explaining the heterogeneity and differential progression observed in OA across different disease stages, affected joints, and individuals

Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, Slagboom PE, Heijmans BT
