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Emerging evidence further indicates that MTs particularly MT1 and MT2A constitute a critical cytoplasmic defense layer against cuproptosis by acting as effective copper sponges that sequester excess Cu + and restrict its aberrant interaction with mitochondrial targets 170,173,174

Other typical substrates for GSTs are pesticides, industrial intermediates, carcinogens, and environmental contaminants

Hover, B

3) SIRT1 attenuates the performances of pre-eclampsia in animal models

It also encompasses peripheral health conditions influenced by the brain, such as obesity and aging
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