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De Rose DU, Pugnaloni F, Cal M, Ronci S, Caoci S, Maddaloni C, et al

Blood probes were taken before and after 1, 2, 3, 4, 24 and 48 h from ALA administration for the cAMP measurements and ALA plasma levels by pharmacokinetic analysis

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Cardiopulmonary bypass (CPB) is related to multiple effects that may contribute to post-operative myocardial injury and cardiac dysfunction, including ischemiareperfusion injury after removal of the aortic clamp, the subsequent generation of reactive oxygen species, and increased production of inflammatory mediators [2, 3]