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Description
Odonkor C

Childhood epilepsy and autism spectrum disorders: psychiatric problems, phenotypic expression, and anticonvulsants

This topic is of great relevance for MB as germline mutations are 5-6% and these genetic alteration affect specific molecular pathways leading to tumor development (75)

This is the case with PKU (PhenylKetoneUrea) where those affected lack an enzyme needed to break down the amino acid (protein letter) phenylalanine (Phe, F)

Acetylated RBPJ binds to the promoter of MCM4, inhibiting the expression of the MCM4 gene
