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It typically presents as progressive Parkinsonism and motor dysfunction, including bradykinesia, rigidity, dysarthria, dystonia, gait and coordination disturbances, tremor, and, in severe cases, prominent psychotic symptoms 258

Weight loss -13.7% vs -3.4% placebo

doi:10.3748/wjg.v23.i36.6650 Mrtensson, J., Jain, A., & Meister, A

Sequential versus simultaneous initiation : Many clinicians prefer establishing tirzepatide tolerance and efficacy before adding other therapies, allowing clearer attribution of benefits and adverse effects

These findings suggest that ITM2B inhibition induced by exposure to electromagnetic fields may constitute a relevant molecular mechanism linking environmental factors with neurodegenerative diseases (23)