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Under the same conditions, treatment with the current drug of choice, PZQ, or the clinically tested and now discontinued meclonazepam (MZM) 42 , which have different schistosomicidal mechanisms and do not inhibit TGR, resulted in no change of that ratio

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Moreover, activation or inhibition of ferroptosis using a variety of ferroptosis initiators and inhibitors can modulate disease progression in animal models