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Description
The cause is usually a mystery , which is why they call it idiopathic

Secondary erythromelalgia from polycythemia vera responds dramatically to low-dose aspirin in some cases providing complete symptom relief

PLoS ONE 2012;9:e45979

This is consistent across the GLP-1 class semaglutide and tirzepatide users report the same pattern

This optional anti-nausea medication can help with side effects