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Fatty acids prevent hypoxia-inducible factor-1alpha signaling through decreased succinate in diabetes

73 Arg78 of NPRL2 serves as the arginine finger responsible for the GAP activity of GATOR1

Abstract High blood pressure (BP) is a significant contributor to the disease burden globally and is emerging as an important cause of morbidity and mortality in the young as well as the old

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Moreover, our evidence indicates that the HEM derived compounds, HeA and HeS, act as active small molecules to promote OL maturation in culture and myelination in ex vivo cerebellar slice culture
