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The mechanism may be related to curculigoside significantly reducing AD-promoting factors (e.g., A1-42, p-tau) and increasing ferroptosis protective factors (e.g., GPX4, SLC7A11, GSH) in the hippocampus and cortex of AD mice, 574 suggesting that the natural compound curculigoside can be used as a promising therapeutic agent to improve AD by inhibiting ferroptosis

Furthermore, feeding mice a glycine-enriched diet was associated with nearly 100% synthesis of l-serine in the canine kidney (92)

doi: 10.3390/ijms24054707

Enhanced ZnR/GPR39 Activity in Breast Cancer, an Alternative Trigger of Signaling Leading to Cell Growth