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established that T4 is indistinguishable from the platelet actin-sequestering peptide Fx, forming a 1:1 complex with actin monomers and inhibiting salt-induced polymerization

The elevated glycolytic flux and the decrease in pentose-phosphate flux suggest that Pink1-deficient neurons suffer a glucose metabolism reprogramming from mitochondrial oxidative to glycolytic metabolism compromising the PPP (Requejo-Aguilar et al., 2014)
10.1007/s00253-021-11622-2 112 DobbsS
The American Journal of Gastroenterology

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