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Mitochondria also showed dysfunction following ischemia reperfusion as characterized by decreased oxygen consumption rates, decreased ATP production, and increased mitochondrial membrane depolarization ( m) [41]

Many forms of carnitine exist, including L-carnitine, acetyl-L-carnitine, propionyl-L-carnitine, and L-carnitine-L-tartrate

Int J Mol Sci 20(6):1345

From a mechanistic perspective, these outcomes are mediated by multi-system endocrine adaptations, including suppression of the HPG axis, alterations in insulin and glucose-regulating hormones, reduced triiodothyronine (T3), elevated cortisol, and disruptions in growth hormone (GH) and insulin-like growth factor 1 (IGF-1) signaling [92]
