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For a discussion of guidelines for dyslipidemia in children and adolescents see the Endotext chapter entitled Guidelines for Screening, Prevention, Diagnosis and Treatment of Dyslipidemia in Children and Adolescents (6) and for a discussion of dyslipidemia during pregnancy see the Endotext chapter entitled Effect of Pregnancy on Lipid Metabolism and Lipoprotein Levels (7)

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Contraindications Pregnancy and lactation: individual case reports suggest safety during pregnancy (de Bruyn 2015), however data which mainly include in vivo studies (Xi 2008) are insufficient

Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes

Because the phospholipids are amphipathic, the expected simplest conformation for a small group of phospholipids in an aqueous solution might be a micelle (Figure 6A), but is this the case