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Pitolisant is a histamine-3 (H3) presynaptic antagonist/inverse agonist at histamine-receptors

The results are similar in rabbits and humans [11, 82]

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Finally, we critically evaluate emerging rejuvenation strategies, translational approaches for next-generation therapies, persistent challenges and promising directions for future research

12 Furthermore, minerals and trace elements have essential roles, such as hormone regulation during the menstrual cycle, ensuring proper ovarian function and ovulation, maintaining endometrium health and receptivity for implantation, and regulating oxidative stress via antioxidant processes to prevent damage to cellular structures