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Patients with severe, longstanding deficiency typically require longer recovery periods, with haematological improvement occurring over weeks and neurological recovery potentially taking months

Acute administration effects suggest alternative metabolic mechanisms involving direct effects on cellular oxidative capacity

Hinrichs A, Kessler B, Kurome M, Blutke A, Kemter E, Bernau M, Scholz AM, Rathkolb B, Renner S, Bultmann S, Leonhardt H, de Angelis MH, Nagashima H, Hoeflich A, Blum WF, Bidlingmaier M, Wanke R, Dahlhoff M, Wolf E