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In the end, the authors concluded that the high doses were able to raise the levels of GSH in blood neutrophils and the neutrophil count in the airways, with a significant reduction in elastase activity, the results being justified by the role of NAC in inhibiting the NF-B pathway, causing a reduction in IL-8

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That rises the hypothesis that reduced glutathione produced by cells can exert a direct control on their glycocalix which affect cell adhesion and cell volume

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