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In this study, MIP-1 was the cytokine with the highest sensitivity (92.2%) to discriminate diseased study patients from controls with the optimal cut-off value of 1.385 pg/mL

TNF expression levels are increased after one week of cuprizone-induced demyelination in vivo [224] and TNF / mice showed a delay in demyelination in the cuprizone model [56], consistent with a role for TNF to exacerbate cuprizone-induced demyelination

doi: 10.1038/s41467-021-24367-3

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Role of the GGDEF regulator PleD in polar development of Caulobacter crescentus