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Diabetic peripheral neuropathy (DPN), a common complication affecting over 50% of people with diabetes, poses a significant challenge due to its underdiagnosis

However, modern advancements in supplement formulation have significantly improved the bioavailability of oral B12, making it a more effective option than ever before

5.3.3 Synbiotics Synbiotics, a mixture containing live microorganisms and substrate(s) selectively utilized by host microorganisms that confer health benefits on the host (Swanson et al., 2020), have been employed to improve the diversity and richness of a dysbiotic gut, favor saccharolytic metabolism, reduce serum levels of free IS, improve intestinal permeability and alleviate constipation (Celano et al., 2023

10.1016/j.sjbs.2017.10.017 Saudi J Biol Sci

doi: 108