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In contrast, no significant difference in the expression of all other analyzed ABC transporters was found between these patient groups (Supplementary Fig

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In the cytosol, 5,10-MTHF participates in two different processes as follows: (1) in thymidylate synthesis, where 5,10-MTHF functions as a methyl donor for the conversion of deoxyuridine-5-monophosphate (dUMP) into deoxythymidine-5-monophosphate (dTMP