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Notably, macroautophagy inefficiently clears aggregated -syn, and autophagosome encapsulation may facilitate -syn fibril propagation via exosomes or tunneling nanotubes (TNTs), spreading pathology [167]

Iwai, K

Additionally, it effectively eliminates senescent chondrocytes in vitro and ameliorates pathological changes and collagen deposition in the lungs of mice with pulmonary fibrosis

The case of CLIC proteins is particular since it exists under both a monomeric soluble and an oligomeric transmembrane form

Whereas plain glutathione must be broken down by enzymes to the basic amino acid components for absorption into the cell requiring more energy expenditure to be re-constructed back to reduced glutathione (rGSH)