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ELLILO, A.C

Using codon-randomizing mutagenesis to generate a clone library bearing nearly 80% of all possible amino acid changes, we measured the functional consequences of CBS variation by measuring the effects of selection on allele frequencies during a competitive yeast complementation assay using next-generation sequencing

Examples are hydrogen peroxide (H 2 O 2 ), organic peroxides such as lipid hydroperoxides (ROOH), hypochlorous acid (HOCl) and peroxynitrite (ONOO ) [46]