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Rare risks include copper toxicity, particularly in individuals with underlying conditions such as Wilsons disease (a genetic disorder causing copper accumulation), and theoretical concerns regarding angiogenesis promotion in the context of active cancers

Sun H, Zhou Y, Ren J, Qu X (2018) Carbon Nanozymes: Enzymatic Properties, Catalytic Mechanism, and Applications
Synergistic formulations with other therapeutic agents Integrating curcumin with additional medicinal drugs can augment its effectiveness and expand its therapeutic uses
Lee, C., Kim, J., Shin, S