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They also ran flow cytometry (Annexin V/PI staining) and western blot analysis to measure specific survival and death markers: Bcl-2, Bax, caspase-3, and PARP

Caballero B, editor: Academic Press

Failure of DNA damage repair can result in genomic instability and mutations, and this is also identified as a hallmark of cancer [5]

While joint replacements are often successful, they involve significant surgery, a long and demanding rehabilitation, and the inherent risks of any major medical procedure

Effects vary by person and by overall lifestyle factors
