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A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo

ARNI could mitigate pulmonary damage triggered by PQ via potential antioxidant anti-inflammatory qualities

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Journal of molecular and cellular cardiology

Additionally, research by Yu et al (138) suggests that TSA alleviates cerebral ischemia-reperfusion injury by downregulating TGM2, inhibiting PANX1 expression and suppressing microglial activation and neuroinflammation (TNF-, IL-1 and IL-6), highlighting the multi-target regulation of TSA in the same disease