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GHK-Cu is particularly useful for Fitzpatrick III through VI skin tones because its anti-inflammatory mechanism addresses the inflammatory pathways that drive post-inflammatory hyperpigmentation in melanin-rich skin
Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies
The peptide diffuses inward on its own
