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The funders had no influence on data analysis

These findings emphasize the need for metabolome-resolved clinical trials, where CRISPR-edited organoids model patient-specific mutations in ACMSD to enhance NAD + salvage, while spatial lipidomics can track the dissemination of arachidonic acid cascades from peri-infarct neurons to distant renal tubules

PV, portal vein

doi:10.1007/s11325-024-03107-z Shea S, Lionis C, Kite C, et al

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