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Elevated NNMT gene expression is notably observed in the liver and white adipose tissue (WAT) of individuals with diabetic mice, obesity, and rats afflicted with MetS

Another clinical trial, sponsored by the Memorial Sloan-Kettering Cancer Center of New York, USA, was also initiated in 2012, in adult -thalassemia major patients receiving autologous CD34 + cells, with non-myeloablative conditioning, after transduction with the TNS9.3.55 LV from the Sadelain group (clinicalTrial.gov identifier: NCT01639690) [171], [173]

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