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The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper

This enzyme catalyzes the cleavage of the high-energy thioester bond in succinyl-CoA, similar to that in acetyl-CoA

doi: 10.1007/s00408-020-00408-4

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As the upregulation of p21 Cip1/WAF1 protein levels was no longer evident transfecting a dominant-negative form of c-fos (DN/c-fos) in both SkBr3 and Ishikawa cells (Figures 5c and d), we ascertained by chromatin immunoprecipitation assay that LA induces the recruitment of c-fos to the AP1 site located within the p21 Cip1/WAF1 promoter sequence (Figure 5e)