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In osteoarthritis, a few studies suggest benefit comparable with standard medications, but a panel could not recommend it for pain
The pathogenesis of necrosis is not known completely
9.3.2 In vivo animal studies Physiological estrogen replacement alleviates menopausal symptoms and may improve sexual dysfunction associated with vaginal dryness, dyspareunia, and decreased libido (251)
Melatonin and melatonergic drugs on sleep: possible mechanisms of action
