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doi: 10.1016/j.fertnstert.2003.10.034

Train-test separation is also the highest for MaxMin split, meaning that not only its test set covers the chemical space of the dataset well, but also at the same time is not too similar to training compounds

Activated microglia in MS and EAE are associated with the production of several pro-inflammatory cytokines (IL-6, IL-1, IL-18, IL-12, IL-23, TNF-) and chemokines (CCL2, CCL3, CCL4, CCL5, CCL7, CCL12) (135)

Herein, we focus on some of the primary lung antioxidant defenses implicated in animal models of pulmonary fibrosis and humans with IPF, including catalase, glutathione (GSH), and superoxide dismutase (SOD) as well as nuclear factor erythroid 2-related factor 2 (Nrf2), the primary regulator of antioxidant enzymes

EMBO J (2017) 36(10):130215.10.15252/embj.201696151 9 TarditoSOudinAAhmedSUFackFKeunenOZhengLet alGlutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma