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PMID 35691683

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These include vitamin B12 deficiency and malabsorption that is caused by the following medical conditions, according to the NIH [1]: Pernicious anemia Tropical sprue Pancreatic insufficiency Surgery in the gastrointestinal tract Certain medications Deficiency in the diet Side effects of B-12 injections Also, according to the NIH, vitamin B-12 injections have some potential side effects, including [1]: Diarrhea Itching Swelling Risk of allergic reaction and anaphylaxis Can Vitamins Aid in Weight Loss

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For general educational context, the principles that apply to reconstituted lyophilised injectable medicines in regulated settings include: Refrigerated storage : Reconstituted solutions are typically stored at 28C unless the SmPC specifies otherwise