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These responses are mediated by the same ligand acting on the same binding site of the receptor, but the high-gain effect is nearly saturated even at concentrations which just begin to elicit the lower gain effect

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[DOI] [Google Scholar] Geissler P

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They are short chains of amino acid monomers linked by covalent bonds

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Differences in the signaling pathways of (1A)- and (1B)-adrenoceptors are related to different endosomal targeting

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Geological Survey, this is critical for life on Earth it is why fish and other aquatic life can survive through winter instead of being frozen solid

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