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Moreover, by attenuating MAPKERK and PI3K/Akt/mTOR signalling cascades (Figures 46), silymarin reduces oxidative stress, thereby prolonging hepatocellular survival and optimising pharmacokinetic stability through improved metabolic resilience

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References Gupta SC, Kismali G, Aggarwal BB

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Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimers disease and related dementias

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