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Moreover, by attenuating MAPKERK and PI3K/Akt/mTOR signalling cascades (Figures 46), silymarin reduces oxidative stress, thereby prolonging hepatocellular survival and optimising pharmacokinetic stability through improved metabolic resilience

References Gupta SC, Kismali G, Aggarwal BB

Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimers disease and related dementias

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