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Inducing ferroptosis or treating with IFN- in Institute of Cancer Research (ICR) mice exacerbates the symptoms of SS, while inhibition of ferroptosis or the IFN- signaling pathway in non-obese diabetic (NOD) mice models alleviates both ferroptosis in the salivary gland and SS symptoms

iv) The reference group composed of 6 rats (CAR + INDO), which received daily injections of indomethacin, as a reference compound, for 10 days then carrageenan

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The anti-tumor effects of metformin on ovarian cancer are attributed primarily to its ability to inhibit cancer cell proliferation, enhance the sensitivity of cancer cells to chemotherapeutic agents, modulate the cell cycle, and promote apoptosis in cancerous cells

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