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The conclusions from these essentially negative MR findings have, however, been questioned in a well-argued critique 31 , pointing out the limitations of genetic markers that explain only a small component (i.e., 7.7% at most 5 ) of serum UA variance and querying whether the core assumptions of MR, including the absence of confounds as well as a strong association with UA, are met

On the plus side, nanosized delivery systems made of advanced biological or synthetic materials hold great promises for precise targeting and controlled release of anti-inflammatory drugs in injured lungs

Whilst high B12 itself is not typically harmful, it may indicate an underlying condition requiring investigation and management

doi: 10.1016/j.freeradbiomed.2023.02.007 [DOI] [PMC free article] [PubMed] [Google Scholar] 132

Breton C, Pechoux C, Morel G, Zingg HH (1995)