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Acknowledgements The authors are supported by US NIH grants R01-DK55758, R01-DK099110, R01-DK127274, R01-DK143576 and R01-DK131537 and P01-AG051459 to P.E.S
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Because it has an impact on levels of the neurotransmitter glutamate in the brain, NAC for anxiety, depression and other mental health conditions may be a useful complementary treatment
The primary outcome was pain intensity after 4 months of treatment
