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Oxidant species and electrophiles are able to increase the transcription of both the modulatory and catalytic subunits (Shi et al., 1994

PMID 10369661

Inducible expression of the g-glutamylcysteine synthetase light subunit by t-butylhydroquinone in HepG2 cells is not dependent on an antioxidant-responsive element
Patients with low glutathione levels may experience: Many chronic health conditions are associated with low glutathione levels, including autoimmune diseases, heart disease, and skin disorders, to name a few
