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Xia N, Daiber A, Forstermann U, Li H
10.1038/nrm2256 Nat
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reported that serum IS levels were positively correlated with H 2 O 2 and Cu/Zn SOD levels, implying that IS triggers oxidative stress in CKD patients [130]
Since the METIV-HCC trial selected patients with high c-Met levels, this does not necessarily mean that tivantinib has no role in targeted treatment in HCC patients
